MIND Foods and Aerobic Training in Black Adults With HTN

Launched by INDIANA UNIVERSITY · Nov 20, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how the MIND diet and aerobic exercise can help improve thinking and memory in Black adults with high blood pressure. The researchers are comparing two groups: one group will receive food delivery and cooking support along with exercise training, while the other group will receive regular care. The goal is to see if these changes in diet and exercise can positively affect brain function.

To participate, you need to be between 35 and 75 years old, live in Marion County, and identify as Black or biracial. You should have a history of high blood pressure and be able to participate in physical activity safely. If you join, you'll take part in cognitive tests, blood pressure monitoring, and may have the option to provide a blood sample for additional research. This trial is recruiting participants now, so if you're interested, it's a great opportunity to contribute to important research while focusing on your health!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Fluent in English
• • 2. Marion County resident
• • 3. 35-75 years
• • 4. Self-identified non-Hispanic and Black/African-American/biracial including African-American
• • 5. Systolic BP of ≥140 in prior 12 months from a primary care visit
• • 6. Ability to see and read street signs (self report)
• • 7. Stable housing with independent access to kitchen, including functional stove or hotplate, oven, refrigerator, and freezer (self report)
• • 8. Activity independence per functional activities questionnaire (FAQ; \<3 responses of "Require Assistance" and 0 responses of "Dependent")
• • 9. Normal cognition per six-item screener (SIS; score of ≥ 5)
• • 10. Less than 20min on usual day of moderate or vigorous physical activity
• • 11. Able to exercise safely per abbreviated Exercise Assessment for You (EASY) or primary care provider clearance
• • 12. Mean systolic BP of ≥130 from 3 standard BP measurements taken by research staff following standardized wait periods.
• Exclusion Criteria:
• • 1. lives in nursing home
• • 2. diagnosis of dementia or Alzheimer disease or mild cognitive impairment; Parkinson disease; brain tumor/infection/surgery (within the last 10 years with residual symptoms and/or functional loss/deficit, such as impaired learning, memory, or communication); cancer with short life expectancy, or current chemotherapy or radiation therapy; psychosis, schizophrenia, or bipolar disorder
• • 3. ICD 10 code I11/hypertensive heart disease, ICD 10 code I12/hypertensive CKD, ICD 10 code I13/hypertensive heart disease and CKD, ICD 10 code I15, or ICD 10 code I16
• • 4. current or past prescription of donepezil, memantine, rivastigmine, or galantamine
• • 5. alcohol consumption ≥ 8 drinks per week for women, or ≥15 drinks per week for men
• • 6. drug use/abuse (excluding marijuana) per EMR
• • 7. moving out of area during study timeline
• • 8. scheduling conflicts with intervention schedule
• • 9. unwilling to use a touchscreen
• • 10. unwilling to be on video conferencing
• • 11. low communicative ability, functional status, or other disorders (examiner rated) that would interfere with interventions and assessments
• • 12. unable to provide informed consent
• • 13. participation in any lifestyle modification/weight loss program (e.g., Weight Watchers, etc.)