Glycemic and Insulinemic Response of Durum Wheat Bread

Launched by UNIVERSITY OF UDINE · Nov 28, 2023

Keywords

ClinConnect Summary

Worldwide, the number of people suffering from type 2 diabetes is around 422 million, and this number is continuously rising. It is globally agreed that, by 2025, serious action against the spread of this disease must be taken, also because diabetes is a major cause of the development of cardiovascular diseases. The spread of diabetes in the last decades is the result of a global rise in obesity, a more sedentary lifestyle, and an energy-dense diet, given the overconsumption of mainly highly digestible starchy food. Among highly digestible starchy foods, bread is a staple food consumed dail...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 18-50 years old;
• • Have good general health;
• • Have normal smell and taste functions;
• • Have a normal body mass index (BMI 18.5-24.9 kg/m2) (based on self-reported weight and height).
• Exclusion Criteria:
• • Have dental braces or a piercing in or around the mouth (except removable piercings);
• • Use medications known to affect glucose tolerance and influence digestion and absorption of nutrients (excluding oral contraceptives) - stable doses of oral contraceptives, acetylsalicylic acid, thyroxin, vitamins, and mineral supplements or drugs to treat hypertension are acceptable.
• • Have a known history of diabetes mellitus or the use of antihyperglycemic drugs or insulin to treat diabetes and related conditions;
• • Have a major medical or surgical event requiring hospitalization within the preceding 3 months;
• • Have any food allergy or intolerance for gluten;
• • Being pregnant or lactating (self-reported);
• • Use medication that may affect the function of taste, smell, mastication, and salivation;