Curcuma Xanthorriza Roxb. 10% Cream for Melasma

Launched by UNIVERSITAS PADJADJARAN · Nov 22, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new cream made from Curcuma xanthorriza Roxb., a plant native to Indonesia, to see if it can help reduce melasma, a condition that causes dark patches on the skin, particularly on the face. Melasma can be difficult to treat, and many current treatments can have side effects or don’t work well. The researchers want to find out if a 10% Curcuma xanthorriza Roxb. cream is effective in lightening these dark patches and improving overall skin brightness.

To participate in this trial, you need to be diagnosed with a specific type of melasma and have visible dark patches on both sides of your face. Unfortunately, if you have had certain treatments recently or have specific health conditions, you may not be eligible. Participants will apply the cream and will be monitored for results, helping researchers understand if this new treatment could be a safe and effective alternative for managing melasma. If you or someone you know is interested, it could be an opportunity to contribute to important research in skin health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Females and males diagnosed with epidermal-type melasma clinically and through Wood's lamp examination.
• • Study subjects exhibit melasma lesions on both sides of the face.
• Exclusion Criteria:
• • History of hypersensitivity to Curcuma xanthorriza Roxb. or kojic acid based on anamnesis.
• • Pregnant and breastfeeding women.
• • Patients using hormonal contraceptive drugs in the last 3 months.
• • Patients using topical medications (depigmentation agents, tretinoin, or corticosteroids) in the skin area to be tested in the last 2 weeks.
• • Patients using systemic corticosteroids in the last 1 month.
• • Patients undergoing laser therapy, microdermabrasion, chemical peels, and other aesthetic procedures in the skin area to be tested in the last 1 month.
• • Patients experiencing inflammation on the facial skin.