Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivity: a Randomized Clinical Trial
Launched by CAIRO UNIVERSITY · Nov 24, 2023
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying two different types of dental varnishes to help manage dentin hypersensitivity, which is a painful condition that many people experience when their teeth become sensitive to hot, cold, or sweet foods. The trial will compare a new varnish called Giomer with a well-known varnish called CPP-ACP to see which one works better in reducing sensitivity. Dentin hypersensitivity is quite common, especially among young adults aged 18 to 40, with about 43% of people in this age group reporting this issue.
To participate in the trial, you need to be between 18 and 40 years old, maintain good oral hygiene, and be experiencing pain from dentin hypersensitivity in at least one tooth. Unfortunately, if you have received desensitizing treatments in the past six months, are taking anti-inflammatory medications, are pregnant, or are a smoker, you won't be eligible to join. If you qualify and decide to participate, you can expect to receive one of the two varnishes during the study and help researchers learn more about effective treatments for dentin hypersensitivity.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Participants of both genders aged 18 to 40 years with good oral hygiene, suffering from pain due to dentin hypersensitivity in at least one tooth
- Exclusion Criteria:
- • Taking desensitizing treatment in the last 6 months. (It affects the outcome)
- • Taking anti-inflammatory drugs. (It affects the hypersensitivity perception)
- • Pregnant females. ( They complain from nausea and repeated vomiting attacks)
- • Smokers. (Smoking will affect the oral hygiene and periodontal health)
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported