The Role of NK Cells to Detect Blood Infection in ALL.

Launched by ASSIUT UNIVERSITY · Nov 29, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how special immune cells called NK cells (natural killer cells) can help detect and understand blood infections in children and young adults with a type of cancer called Acute Lymphoblastic Leukemia (ALL). The researchers want to see if profiling these NK cells can predict blood infections and if they play a role in how some patients become resistant to chemotherapy drugs after treatment.

To be eligible for this study, participants must be under 17 years old, have been diagnosed with ALL, and currently be undergoing chemotherapy while also having a blood infection. Unfortunately, those over 17 or who have other blood cancers won't be able to join. If you or someone you know qualifies, participants will undergo tests that analyze their NK cells to help improve treatment and detection of infections in the future. This trial is not yet recruiting, so there’s still time to learn more before it starts.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged less than 17 years diagnosed as Acute Lymphoblastic Leukemia and on chemotherapy, who are positive for blood stream infection.
• Exclusion Criteria:
• • 1. Patients over 17 years of age.
• • 2. Presence of other hematological malignancies or history of other malignancies.