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Search / Trial NCT06161142

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology

Launched by UNIVERSITY OF BONN · Dec 5, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Hypophosphatasia Hypophosphatasemia Musculoskeletal Complaints Rare Disease Genetic Disorder Alkaline Phosphatase Gene Alp Alp Gene Rheumatic Disease Cohir Study Prevalence Diagnostic Algorithm Metabolic Bone Diseases

ClinConnect Summary

This clinical trial is looking into a condition called hypophosphatasia, which is often missed or misdiagnosed in adults. The study aims to find out how common hypophosphatasia is among adult patients who visit rheumatology clinics. Researchers want to create a way to help doctors spot this condition earlier, which could lead to better treatment options.

To participate in the trial, individuals must be over 18 years old and have a doctor who suspects they might have hypophosphatasia. They also need to have certain lab results that indicate a problem with a specific enzyme called alkaline phosphatase. If those criteria are met, participants can expect to contribute to important research that may improve the way hypophosphatasia is diagnosed and treated in the future. This study is currently recruiting participants of all genders.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Written Informed consent
  • Age \> 18 years
  • Clinical suspicion of hypophosphatasia
  • Evidence of a pathological ALP value within the clinical routine screening
  • Exclusion Criteria:
  • Failure to meet the inclusion criteria listed above

About University Of Bonn

The University of Bonn is a renowned academic institution dedicated to advancing medical research and education. With a strong emphasis on interdisciplinary collaboration, the university engages in cutting-edge clinical trials aimed at improving patient outcomes and advancing healthcare knowledge. Its comprehensive research programs are supported by state-of-the-art facilities and a commitment to ethical standards in clinical practice. By fostering partnerships with healthcare professionals and industry leaders, the University of Bonn plays a pivotal role in translating scientific discoveries into innovative therapeutic solutions.

Locations

Bonn, North Rhine Westphalia, Germany

Patients applied

0 patients applied

Trial Officials

Valentin S. Schäfer, Dr. med.

Principal Investigator

University Hospital of Bonn

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported