Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial

Launched by UNIVERSIDAD NACIONAL AUTONOMA DE HONDURAS · Dec 1, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of cinnamon, specifically an extract called Cinnamomum verum, to help start labor in women who are having their first baby. The researchers want to see if this natural substance can effectively initiate labor, as it has been traditionally used for this purpose, but hasn't been scientifically proven yet. Participants in this study will be women aged between 18 and 35 who are nearing the end of their pregnancy (between 37 to 41 weeks) and are in good health. They should also be willing to take cinnamon capsules as part of the trial.

If you decide to participate, you'll be asked to sign a consent form and follow the study guidelines for the duration of the trial. The trial is currently recruiting participants in Tegucigalpa, and it's important that you do not have certain health conditions or be taking specific medications that could affect the study's results. Overall, this trial aims to explore a natural approach to aid in labor, which could provide new options for expecting mothers.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Delivery of an informed consent form signed and dated by parents or guardian and patient
• • 2. Declared willingness to comply with all study procedures and availability for the duration of the study.
• • 3. provision of appropriate consent and assent
• • 4. Willingness and ability to participate in study procedures
• • 5. Patients under 18 years of age
• • 6. Full-term pregnancies (37-41 Weeks of Gestation).
• • 7. Nulliparity
• • 8. Have your own cell phone
• • 9. Know how to read and write
• • 10. Residing in Tegucigalpa
• • 11. Be in good general health, as evidenced by your medical history
• • 12. Ultrasound with amniotic fluid index \> 5 cm
• • 13. Non Stress Test Reactive
• • 14. Ability to take oral medication and be willing to comply with the cinnamon capsule regimen
• Exclusion Criteria:
• • 1. Current use of antihypertensive or hypoglycemic medications
• • 2. Presence of non-curable chronic diseases prior to pregnancy or during pregnancy such as hypertension, diabetes, hypothyroidism
• • 3. Premature rupture of membranes
• • 4. Infections (urinary tract infection, chorioamnionitis) present at the time of the study (diagnosed with symptoms or leukocytes \>12,500 or pathological urine examination)
• • 5. Allergies to cinnamaldehyde or cinnamon, canola oil
• • 6. Multiple pregnancy
• • 7. Major fetal malformations
• • 8. Fetal death
• • 9. Non-cephalic presentation
• • 10. Severe oligohydramnios (amniotic fluid index \< 2 cm)
• • 11. Having consumed or being consuming cinnamon products 7 days before the start of the study
• • 12. Febrile illness within 7 days before starting to take cinnamon
• • 13. Treatment with another investigational drug or other intervention within 7 days prior to the start of the intervention
• • 14. Current smoker or tobacco use