Breisgau Pheno Heart Study

Launched by UNIVERSITY HOSPITAL FREIBURG · Dec 4, 2023

Keywords

ClinConnect Summary

The Breisgau Pheno Heart Study is a clinical trial aimed at better understanding how the immune system reacts after a heart attack (myocardial infarction), specifically focusing on two types: STEMI and NSTEMI. Researchers want to learn how the immune response can affect recovery and lead to complications like heart failure or irregular heartbeats. By studying patients who have had a heart attack, the trial hopes to identify specific blood markers that could help predict which patients are at higher risk for these serious issues. This information could ultimately guide better treatment approaches in the future.

To participate in this study, patients must be over 18 years old and have recently experienced a heart attack that required emergency treatment. They will undergo several follow-up visits over the next year, during which their health will be closely monitored through various tests and blood samples. Participants will receive a detailed examination and be asked to share their health history, contributing to a comprehensive understanding of recovery after a heart attack. It's important to note that certain health conditions or circumstances may disqualify someone from participating, such as severe anemia or active infections.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Emergency coronary angiography and age\>18 years and STEMI or NSTEMI or "none of these diseases"
• Exclusion Criteria:
• • Hemoglobin\<7,0 g/dl
• • Platelets \<50.000/µl
• • Unable to provide written informed consent
• • Age \> 80 years
• • hematological neoplasia
• • metastasized cancers
• • acute infection (z.B. Sepsis)
• • Chronic Inflammatory conditions (z.B. inflammatory bowel disease, Rheumatoid arthritis, chronisch hepatitis)
• • Pregnancy
• • Immunosuppression
• • Resuscitation \>5 min oder mehr als 1x Defibrillation vor Koronarangiographie
• • Cardiogenic shock
• • Mechanical circulatory support
• • Cardiomyopathy with an left ventricular ejection fraction F \<40% before the event
• • Dialysis
• • Cirrhosis \> CHILD-A
• • Not living in the county of Breisgau-Hochschwarzwald or Emmendingen oder planned relocation
• • Alcohol and drug abuse
• • Non-compliance