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Search / Trial NCT06166706

Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia

Launched by ACADEMISCH MEDISCH CENTRUM - UNIVERSITEIT VAN AMSTERDAM (AMC-UVA) · Dec 4, 2023

Trial Information

Current as of July 21, 2025

Recruiting

Keywords

Pediatric Anesthesia Postoperative Pulmonary Complications Mechanical Ventilation

ClinConnect Summary

This clinical trial is looking at how children are ventilated (helped to breathe) during and after surgery with general anesthesia. Researchers want to understand the different ways that machines are used to assist children's breathing and how these methods might lead to problems with their lungs after the surgery. They hope to find better guidelines for doctors to follow, which could help reduce the chances of complications that may require a longer hospital stay and increase costs.

To be eligible for this study, children must be 16 years old or younger, undergoing general anesthesia, and require help with their breathing using a tube or a special device. Participants will be monitored during their procedure to see how the different ventilation strategies affect their recovery. It’s important to know that some children will not be able to participate, such as those undergoing certain types of surgeries that involve complex breathing support. Overall, this trial aims to improve the safety and effectiveness of breathing assistance for children during surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • aged ≤ 16 years;
  • undergoing general anesthesia
  • airway management with tube or LMA; and
  • connected to mechanical ventilator . minimum duration of procedure: 15 minutes
  • Exclusion Criteria:
  • patients undergoing surgical procedures involving extra-corporal circulation;
  • patients receiving ventilation with high frequency jet ventilation or high frequency oscillatory ventilation;
  • sedation without airway management in the form of a endotracheal tube or a supraglottic airway device; and
  • (rigid) bronchoscopic procedures with maintenance of spontaneous ventilation.

About Academisch Medisch Centrum Universiteit Van Amsterdam (Amc Uva)

The Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) is a leading academic medical center in the Netherlands, dedicated to advancing healthcare through innovative research, education, and patient care. Affiliated with the University of Amsterdam, AMC-UvA integrates clinical practice with cutting-edge biomedical research, fostering a multidisciplinary approach to medical challenges. The institution actively engages in clinical trials to enhance treatment options and improve patient outcomes, while promoting collaboration among healthcare professionals, researchers, and academic institutions globally. With a commitment to excellence and a focus on translational medicine, AMC-UvA plays a pivotal role in shaping the future of healthcare.

Locations

Perth, , Australia

Genoa, , Italy

Bern, , Switzerland

Amsterdam, Please Select, Netherlands

Patients applied

0 patients applied

Trial Officials

Marcus Schultz, Prof

Principal Investigator

Amsterdam UMC

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported