Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort

Launched by SEMMELWEIS UNIVERSITY · Dec 3, 2023

Keywords

ClinConnect Summary

The POMODORI study is a clinical trial aimed at understanding how certain health conditions affect female fertility. Specifically, it focuses on women who have polycystic ovary syndrome (PCOS), insulin resistance, obesity, or mitochondrial dysfunction, which are all linked to difficulties in getting pregnant. Researchers are looking to enroll 150 women who have these conditions and an equal number of women without these issues for comparison. The goal is to investigate specific markers in the body that may indicate problems with mitochondria, the energy-producing parts of our cells, which might play a role in infertility.

To be eligible for this study, participants need to be women of reproductive age who have been diagnosed with PCOS, insulin resistance, or a history of infertility related to these conditions. They should be generally healthy and willing to participate. Those who have serious health issues or cannot cooperate will not be included. If you join the study, you can expect to undergo tests that will help researchers learn more about these conditions and how they might affect reproductive health. This research is important as it could lead to better treatments and support for women facing infertility challenges.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Presence of polycystic ovary syndrome (PCOS) or insulin resistance (IR) associated with other multisystemic phenotypes, mitochondrial dysfunction
• • history of infertility associated with other multisystemic phenotypes, mitochondrial dysfunction
• • a known history of mitochondrial dysfunction and PCOS and/or IR
• • general health is good and there is no serious general medical condition that would prevent participation would make participation highly risky
• Exclusion Criteria:
• • poor cooperation
• • refusal to participate in the study