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Search / Trial NCT06169813

E-cigarette Harm Reduction Among PLWHA in South Africa

Launched by NYU LANGONE HEALTH · Dec 4, 2023

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial, called "E-cigarette Harm Reduction Among People Living with HIV/AIDS (PLWHA) in South Africa," is looking for ways to help people who smoke regular cigarettes reduce their tobacco use. The study will compare two methods: using e-cigarettes and nicotine replacement therapy (like patches or gum), enhanced with supportive text messages. By focusing on people living with HIV/AIDS, the goal is to find effective strategies that can improve their health and help them live longer, especially since smoking can be more harmful for them.

To participate, you must be an adult smoker who is living with HIV/AIDS and speaks Afrikaans, Xhosa, or English. You should be smoking at least five cigarettes a day and be interested in reducing your cigarette use, even if you're not ready to quit completely. Participants will be required to have a mobile phone, as the program will use text messaging to provide support. This trial is not yet recruiting, but it aims to build better resources for helping smokers in South Africa through innovative telehealth approaches.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult PLWHA CC smokers;
  • Speaks Afrikaans, or Xhosa, or English;
  • reports daily CC smoking (≥ 5 CPD);
  • Owns any type of mobile phone;
  • interested in reducing CC smoking but not necessarily trying to quit;
  • Receives HIV/AIDS care in one of the eight selected clinics follow-up rates.
  • Exclusion Criteria:
  • are pregnant or breastfeeding;
  • unable to provide consent;
  • used tobacco products other than CC in the past 2 weeks (e.g., EC, cigarillo);
  • currently engaged in an attempt to quit CC smoking;
  • current major depressive or manic episode, current psychotic disorder, past-year suicide attempt, or current suicidal ideation with plan or intent. plan or intent.

About Nyu Langone Health

NYU Langone Health is a premier academic medical center located in New York City, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a leading sponsor of clinical trials, NYU Langone Health integrates cutting-edge scientific inquiry with patient-centered care, striving to develop new therapies and improve health outcomes across a wide range of medical conditions. The institution is dedicated to fostering collaboration among researchers, clinicians, and patients, ensuring rigorous adherence to ethical standards and regulatory guidelines in all clinical research initiatives. By leveraging its extensive resources and expertise, NYU Langone Health aims to contribute significantly to the advancement of medical knowledge and the enhancement of patient care.

Locations

New York, New York, United States

Cape Town, , South Africa

Patients applied

0 patients applied

Trial Officials

Omar El-Shahawy

Principal Investigator

NYU Langone Health

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported