The Study on the Effectiveness and Safety of Electroacupuncture at ST36 in Treating Primary Premature Ejaculation

Launched by THE AFFILIATED NANJING DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL · Dec 7, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating whether a treatment called electroacupuncture, specifically at a point known as ST36, can help men with primary premature ejaculation (PE). Primary premature ejaculation is when a man often ejaculates within one minute of starting sexual intercourse, which can lead to feelings of anxiety, frustration, and avoidance of sexual activity. The study is currently looking for male participants aged 18 to 60 who have been in a stable relationship for more than six months and experience these symptoms.

To join the trial, participants must not have certain health issues, such as infections, hormonal imbalances, or other serious medical conditions. They also should not have recently taken specific medications that could affect the study's results. If eligible, participants can expect to receive electroacupuncture treatment and will be monitored to see how well it works and whether it is safe. This study is important as it may offer a new approach to treating premature ejaculation, helping men improve their sexual health and overall well-being.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18 to 60
• • 2. Heterosexual, with a single, stable partner for more than 6 months
• • 3. Symptoms of primary premature ejaculation: Complaints of IELT ≤ 1 min since the first sexual intercourse, and poor ability to control ejaculation leading to anxiety, annoyance, depression or/and avoidance of sexual life and other negative effects.
• Exclusion Criteria:
• • 1. Urinary system infection: Urinary tract infection symptoms (such as urinary tract irritation symptoms, prostatitis symptoms, blood semen, etc.) or urine routine shows abnormal white blood cells and red blood cells
• • 2. Abnormal androgen: sex hormone examination shows abnormal androgen (testosterone)
• • 3. Systemic diseases: ask about medical history of hypertension, diabetes, alcohol dependence, coronary heart disease and mental disorders
• • 4. Organic abnormalities: Abnormal development of external genitalia, bilateral testes, epididymis and spermatic cords with obvious abnormalities on palpation
• • 5. History of surgery and trauma: Dorsal nerve block of the penis, erectile function-related surgery, prostate surgery, pelvic surgery, etc.
• • 6. Influence of drugs: within one month before enrollment, have taken SSRI, tramadol and other drugs to treat diseases
• • 7. Allergy to dapoxetine and lidocaine
• • 8. History of drug, alcohol or substance abuse in the past 6 months
• • 9. Accompanied by erectile dysfunction: International Index of Erectile Function-5 (International Index of Erectile Function, IIEF-5) score ≤ 21 points