Evaluation of the Response to Hypoxia at Rest and During Exercise in a Healthy Subject After a Cryostimulation Exposure

Launched by POITIERS UNIVERSITY HOSPITAL · Dec 8, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating how repeated exposure to very cold temperatures (cryostimulation) affects the body’s response to low oxygen levels (hypoxia) during exercise. The researchers want to understand how these two conditions interact and how they might help improve our physical performance. Specifically, they are looking at changes in how our bodies use oxygen when we exercise in low-oxygen environments, which can help in creating better training strategies for athletes and others exposed to these conditions.

To participate in this study, you need to be a healthy male aged between 65 and 75 years who stays physically active according to World Health Organization guidelines. You should not have had any exposure to cold or low-oxygen conditions in the past three months, and you should not have any chronic medical conditions or respiratory issues. If you join the study, you will undergo a series of tests and exercises while being monitored for how your body responds to the cold and low-oxygen conditions. This research is important as it can help us better understand how our bodies adapt to different environmental challenges.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Having a high level of physical activity according to the criteria of the World Health Organization, assessed using the Global Physical Activity Questionnaire (GPAQ);
• • No exposure to cryostimulation or hypoxia (FiO2 13.5%, equivalent to an altitude of 3500 m) in the last 90 days;
• • No planned sports competition during the 4 weeks of the protocol;
• • Maintaining a stable physical activity level (regular training, without interruption or specific competition, including sports training programs) anticipated for 4 weeks;
• • No history of respiratory conditions (asthma, respiratory allergies, exercise-induced asthma, exertional dyspnea);
• • Absence of any chronic medical condition;
• • No ongoing medication treatments;
• • Covered by a French Social Security;
• • Informed consent, signed by the subject after clear and fair information about the study.
• Exclusion Criteria:
• • Subject under treatment;
• • Simultaneous participation in another clinical research study;
• • Individuals with enhanced protection, namely minors, individuals deprived of liberty by judicial or administrative decision, persons staying in a healthcare or social facility, adults under legal protection, and finally, patients in emergency situations;
• • Subject presenting a contraindication to hypoxia and/or cryostimulation.