Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids

Launched by UNIVERSITY HOSPITALS OF NORTH MIDLANDS NHS TRUST · Dec 15, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring a new treatment option for people suffering from hemorrhoids, specifically looking at a procedure called trans-radial superior rectal artery embolisation. This method is already used in emergency situations for bleeding hemorrhoids, but this study aims to see if it can also be safely used for patients who are not in an emergency and want to avoid traditional surgery. The trial will include 20 patients who have recurring or active bleeding from grade II to IV hemorrhoids, and who either do not want surgery or have already had surgery without success.

Participants in this study will undergo a procedure that takes place in a day and is done under local anesthesia, meaning they will be awake but won’t feel pain in the area being treated. They will be monitored for 24 months after the procedure to assess how well it works and how safe it is. It’s important to note that people who have certain health conditions, are pregnant, or have had allergic reactions to contrast dye used in imaging will not be eligible for this study. This research could lead to less invasive treatment options for hemorrhoids, potentially improving care and reducing costs in the healthcare system.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Patients eligible for the study must comply with all of the following prior to enrolment:
• • Patients with grade II-IV haemorrhoid disease with re-current or active bleeding
• • Patients with (i) who do not wish to undergo surgery for their symptoms
• • Patients with (i) despite recent surgery
• • Patients willing and able to give fully informed consent
• • Patients aged ≥18 years
• Exclusion Criteria:
• • Patients who are not otherwise fit for surgery
• • Patients with significant ano-rectal comorbidities (cancer, fistula, abscesses)
• • Patient who are unable to sign the informed consent form.
• • Patients who are pregnant (completed as part of standard IRMER protocol)
• • Patients with history of significant colorectal disease or previous colectomy.
• • Patients with history of an allergic reaction to x-ray contrast
• • Patients who are currently involved in research