Prognostic Value of Exhaled Isoprene Levels for Morbidity and Functional Outcome in Cardiosurgical Patients
Launched by UNIVERSITY OF ROSTOCK · Dec 16, 2023
Trial Information
Current as of August 21, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how levels of a substance called isoprene, which we breathe out, can help predict the health and recovery of older patients undergoing heart surgery. Isoprene is produced by our muscles, and researchers believe that measuring its levels can give insights into a patient's physical strength and overall well-being after surgery. This information could be valuable for identifying patients who might be at higher risk for complications, allowing doctors to take steps to support their recovery better.
To be eligible for this study, participants must be at least 65 years old and scheduled for a planned heart surgery that will take longer than one hour. Those who agree to take part will have their isoprene levels measured before and after the surgery to see how it relates to their recovery. It’s important to note that individuals with certain health conditions, such as severe infections or significant mobility issues, won’t be included in this study. Overall, this trial aims to improve care for older patients by using simple, non-invasive tests to understand their health better.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age \>= 65 years
- • planned cardiac surgery
- • operation duration \>60 min
- Exclusion Criteria:
- • refusal of study participation
- • emergency / urgent surgery
- • acute myocardial infarction
- • acute or chronic infection
- • Pre-existing illness with permanent restriction of mobility
- • Pre-existing neuromuscular disease
- • current malignant disease
- • terminal renal insufficiency
- • severe liver cirrhosis
- • severe obstructive pulmonary disease
About University Of Rostock
The University of Rostock is a prestigious academic institution located in Germany, dedicated to advancing medical research and education. With a strong emphasis on interdisciplinary collaboration, the university is committed to conducting innovative clinical trials that address pressing health challenges. Its research initiatives are supported by state-of-the-art facilities and a team of experienced professionals, enabling the exploration of cutting-edge therapies and interventions. The University of Rostock aims to contribute to the scientific community and improve patient outcomes through rigorous clinical investigation and the dissemination of knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rostock, Mecklenburg Vorpommern, Germany
Patients applied
Trial Officials
Felix Klawitter, Dr. med.
Principal Investigator
Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Rostock University Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported