Efficacy of Oral Hygiene Instructions on Proinflammatory Cytokines Among Cigarette Smokers and Individuals Vaping Electronic Cigarettes During Plaque Induced Gingivitis (Clinical Trial)

Launched by UNIVERSITY OF BAGHDAD · Dec 11, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how oral hygiene instructions can affect certain inflammatory markers in people with gingivitis who smoke cigarettes or use electronic cigarettes (vapes). The main goal is to understand whether vaping impacts levels of inflammation in the mouth compared to traditional smoking and non-smoking individuals who all have gingivitis. Participants will be divided into three groups: those who smoke cigarettes, those who vape, and non-smokers, all with a diagnosis of gingivitis. They will receive guidance on how to improve their oral hygiene, and their levels of specific inflammatory substances will be measured before and after this training.

To be eligible for the study, participants must be male cigarette smokers for at least a year but not more than eight cigarettes a day, or electronic cigarette users with low to medium dependence. They should have at least 20 teeth and show signs of generalized gingivitis, which means they have bleeding gums but no severe gum disease. However, individuals who smoke both cigarettes and vapes, have used tobacco in other forms, or have certain health issues will not be able to participate. If you join, you can expect to learn more about maintaining good oral hygiene and how it might help manage gum inflammation associated with smoking or vaping.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • the included participant will be patients smoking cigarette at least 12 months no more than 8 cigarettes per day, patients use electronic vape in categories of low to medium dependance according to the Penn state electronic cigarette dependence index (one time consist of around 15 puffs or last around ten minutes). participants who never consumed tobacco in any form during their lifetime, having minimum of 20 teeth, additionally, all of involved patients having generalized gingivitis with intact periodontium in which they have more than 10% bleeding sites with no PPD \>3 mm with no clinical attachment loss according to criteria proposed by (Chapple in,2018).
• Exclusion Criteria:
• • dual smokers, smokeless tobacco, heavy smokers, patient using high nicotine formula (more than 25 mg/ml), periodontitis patient, patient with systemic diseases, females, participants who had used antibiotics, steroidal or non-steroid anti-inflammatory drugs within the past 6 months, patients who had undergone periodontal therapy within the last 6 months and patients unwilling to participate in study.