The Influence of Vertical Implant Position on the Marginal Bone Loss in Thick Versus Thin Phenotype.
Launched by CAIRO UNIVERSITY · Dec 11, 2023
Trial Information
Current as of July 09, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how the position of dental implants affects bone loss around the implants, especially in patients with different types of gum tissue thickness. Researchers want to see if placing implants slightly below the gum line (subcrestal position) can help reduce bone loss compared to placing them at the gum line (crestal position). This is important because maintaining healthy bone around implants is key to their long-term success and appearance.
To participate in the trial, you would need to be at least 18 years old and have a single missing tooth in the upper front or premolar area. You should also have enough healthy bone to support the implant and be in good overall health without any conditions that could complicate healing, like certain metabolic diseases or infections. If you decide to join, you'll receive the implant and will need to attend follow-up appointments for a year to monitor your progress. This study could help improve how dental implants are placed in the future, potentially leading to better outcomes for patients.
Gender
ALL
Eligibility criteria
- Eligibility criteria:
- Inclusion criteria:
- • Patients with single missing upper anterior or premolar teeth
- • Patients with minimum buccolingual width of 6 mm and mesiodistal width of 6mm
- • Patients with healthy systemic conditions.
- • Patients older than 18 years.
- • Good oral hygiene.
- • Accepts one year follow-up period (cooperative patients).
- • The patient provides informed consent.
- • Adequate Inter-arch space for implant placement.
- • Favorable occlusion (no traumatic occlusion).
- • Absence of allergy to the prescribed medications.
- Exclusion criteria:
- • Patients with inadequate bone volume and/ or quality
- • Patients with local root remnants
- • Patients with inadequate wound healing
- • Patients with signs of acute infection related to the area of interest.
- • Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits (Lobbezoo et al., 2006).
- • Heavy smokers patients (more than 10 cigarettes per day) (Lambert, Morris and Ochi, 2000).
- • Metabolic diseases such as diabetes or hyperthyroidism as well as systemic medications such as chemotherapy or bisphosphonates
- • Pregnant or nursing women.
- • Uncooperative patients.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Giza, , Egypt
Patients applied
AG
DF
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported