Effect of Maternal Age and BMI on Induction of Labor Using Oral Misoprostol in Late-term Pregnancies: a Retrospective Cross-sectional Study

Launched by UNIVERSITY OF PALERMO · Dec 14, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how a mother's age and body weight (measured by BMI) affect the use of a medication called misoprostol to start labor in women who are late in their pregnancies. Misoprostol is taken orally and is used to help women who are not yet in labor but are past their due dates. The researchers want to learn if these factors can impact the effectiveness of the medication.

To be eligible for this study, women must be pregnant and late-term (meaning they are past 40 weeks) but not yet in labor. They also need to have a specific score that indicates they are ready for labor (known as the Bishop score) that is less than 7. However, women with certain conditions, such as having painful contractions already, medical issues that prevent the use of misoprostol, or complications with the pregnancy, will not be able to participate. This trial is not yet recruiting participants, but it aims to provide valuable information for future pregnancies and labor inductions.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Late term pregnancies out of labor,
• • Bishop score \< 7
• Exclusion Criteria:
• • labor (defined as presence of at least three painful uterine contractions every ten minutes),
• • uterine tachysystole (\>5 contractions within 10 minutes for two consecutive 10-minute periods),
• • hypertonic uterus,
• • abnormal CTG,
• • contraindications to vaginal delivery (fetal malpresentation such as breech presentation or transverse situation, fetal macrosomia, abnormally implanted placenta, active genital herpes infection, cervical cancer),
• • patients with parity \> 4,
• • medical contraindication to misoprostol (asthma, glaucoma),
• • women with previous hysterotomies.