Prone Position With Different Types of Cushions in Patients With ARDS

Launched by HOSPITAL DE CLINICAS DE PORTO ALEGRE · Dec 14, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating how different types of cushions used during a treatment called the "prone position" can help improve lung function in patients with moderate to severe Acute Respiratory Distress Syndrome (ARDS). The prone position involves turning patients onto their stomachs to help with breathing, and the study aims to see if the way these cushions are arranged affects how well the lungs are recruited or engaged during this process.

To participate in this study, individuals must be adults aged 18 and older who have moderate or severe ARDS and are recommended to try the prone position. However, certain health conditions, such as recent surgeries or specific medical emergencies, may make someone ineligible. Participants can expect to be monitored using a technique called Electrical Impedance Tomography (EIT), which helps assess lung function during the treatment. This trial is currently recruiting participants, and it’s a great opportunity for those who meet the eligibility criteria to contribute to important research in ARDS treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients aged 18 years or more, with
• • moderate or severe acute respiratory distress syndrome (ARDS), and
• • indication of prone position
• Exclusion Criteria:
• • Contra-indication to the prone position: intracranial pressure \> 30 mmHg or cerebral perfusion pressure \< 60 mmHg; massive haemoptysis needing urgent surgical or radiological treatment; tracheal or thoracic surgery in the last 15 days; facial trauma or surgery in the last 15 days; deep venous thrombosis or pulmonary embolism treated in the last 2 days; unstable bone dislocations of rachis, femur, rib cage, pelvis; mean systolic arterial pressure less than 70 mmHg despite vasopressive therapy and pregnancy
• • Severe acute respiratory distress syndrome (ARDS) caused b coronavirus disease 2019 (despite meeting the Berlin criteria for ARDS, their ventilatory mechanics are characterized by nearly normal compliance, something rarely seen in patients with ARDS from other etiologies)
• • contraindications for the use of Electrical Impedance Tomography (EIT) such as presence of a cardiac implantable electronic device
• • Pulmonary transplantation
• • Prone position before enrollment