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Search / Trial NCT06189924

Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

Launched by THE INSTITUTE OF MOLECULAR AND TRANSLATIONAL MEDICINE, CZECH REPUBLIC · Jan 2, 2024

Trial Information

Current as of August 22, 2025

Not yet recruiting

Keywords

Exhaled Breath Condensate Proteomics Genomics Mechanical Ventilation Acute Respiratory Failure Lung Injury Intensive Care

ClinConnect Summary

This clinical trial is studying patients who are on mechanical ventilation due to serious breathing problems, like acute respiratory failure. The goal is to collect a small sample of their exhaled breath and blood to analyze changes in their biological markers. By examining these samples, researchers hope to identify patterns that could help detect various health issues early on, which is crucial for better treatment outcomes.

To be eligible for this trial, patients need to be in an intensive care unit and on mechanical ventilation that allows for safe collection of breath samples. The study is not yet recruiting participants, and it is open to all genders within a certain age range. If someone is eligible and agrees to participate, they can expect to have their exhaled breath and blood samples taken in a way that is safe and minimally invasive. This research could potentially lead to improvements in how doctors monitor and treat critically ill patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Intensive care setting Mechanical ventilation Ventilator/ventilator circuit technically suitable for sampling of exhaled breath condensate
  • Exclusion Criteria:
  • Mechanical ventilation challenging to the extent that the insertion of the sampling kit into the ventilator circuit would substantially increase the risk for respiratory deterioration

About The Institute Of Molecular And Translational Medicine, Czech Republic

The Institute of Molecular and Translational Medicine (IMTM) in the Czech Republic is a leading research institution dedicated to advancing the fields of molecular biology and translational medicine. With a focus on bridging the gap between laboratory research and clinical applications, IMTM aims to develop innovative therapeutic strategies and improve patient outcomes. The institute fosters a collaborative environment that brings together experts in various disciplines, including genetics, pharmacology, and clinical research, to drive scientific discovery and facilitate the translation of findings into practical medical solutions. Through rigorous clinical trials and a commitment to ethical research practices, IMTM is at the forefront of enhancing healthcare and addressing unmet medical needs.

Locations

Olomouc, , Czechia

Olomouc, , Czechia

Patients applied

0 patients applied

Trial Officials

Emil Berta, MD PhD

Principal Investigator

IMTM, Palacky University in Olomouc, Faculty of Medicine and Dentistry

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported