Comparison of Aqueous Humor Adipokines in Glaucoma Patients and Healthy Controls

Launched by PEKING UNIVERSITY · Dec 19, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at the differences in certain proteins called adipokines found in the fluid of the eye (aqueous humor) between people with primary open-angle glaucoma (POAG) and healthy individuals who have had cataract surgery. The goal is to see if these proteins could help us understand more about glaucoma and how it differs from healthy eyes.

To join the study, participants need to be at least 18 years old and either diagnosed with POAG or healthy individuals who have recently had cataract surgery. However, people with other eye diseases, recent eye surgery (except for uncomplicated cataract surgery), or certain health conditions like diabetes or mental disorders cannot participate. Participants will undergo tests to measure the levels of adipokines in their eye fluid, helping researchers gather valuable information about glaucoma. If you or someone you know fits the criteria and is interested, this could be a meaningful opportunity to contribute to our understanding of glaucoma.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery).
• Exclusion Criteria:
• • Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded.
• • Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery.
• • History of Ocular Trauma or Inflammation
• • Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded.
• • Pregnancy or Lactation: Females who are pregnant or lactating are excluded.
• • Presence of any retinal or optic nerve disease other than glaucoma.