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Search / Trial NCT06194058

Rapid Sequence Intubation and Hemodynamic Disorders in the Operating Room: a Prospective Multicenter Observational Study

Launched by NANTES UNIVERSITY HOSPITAL · Dec 21, 2023

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

Anesthetic Induction Adult Patients Hemodynamic Disorders Arrythmia Cardiac Arrest Pre Oxygenation Mean Blood Pressure

ClinConnect Summary

This clinical trial is studying how anesthesiologists in France manage a procedure called rapid sequence intubation, which is a method used to quickly place a breathing tube in patients who need general anesthesia. The researchers want to see how well doctors are following the latest expert guidelines and how they handle problems related to blood pressure and heart rhythms that can happen during this process. They will be looking at various practices, equipment, and medications used, as well as any complications that arise within the first 10 minutes after intubation.

To participate in this study, individuals must be at least 18 years old and scheduled for a procedure requiring general anesthesia where rapid sequence intubation will be used. However, people who have certain conditions, such as severe breathing difficulties or low blood pressure before surgery, will not be eligible. If you join the study, you can expect to have your health information monitored closely during and shortly after the intubation process to help improve safety and care in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age ≥ 18 years' old
  • Procedure requiring general anesthesia with oro or nasotracheal intubation
  • Anesthetic management with indication of rapid sequence induction
  • No objection after oral and written information to the patient
  • Exclusion Criteria:
  • Age \< 18 years' old
  • Impossible intubation planned
  • Preoperative respiratory distress (SpO2 \< 90% in ambient air)
  • Preoperative shock (MBP≤ 65 mmHg or vasopressive amines)
  • Preoperative coma defined by a Glasgow score ≤ 12/15
  • Patient in cardiopulmonary arrest
  • Patients under guardianship or curatorship

About Nantes University Hospital

Nantes University Hospital, a leading academic medical institution in France, is dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital integrates cutting-edge scientific exploration with patient care, fostering collaborations among multidisciplinary teams of healthcare professionals and researchers. With a strong emphasis on ethical standards and patient safety, Nantes University Hospital aims to contribute to the development of effective therapies and interventions that enhance patient outcomes and overall public health.

Locations

Villejuif, , France

Lyon, , France

Caen, , France

Lyon, , France

Toulon, , France

Brest, , France

Nantes, , France

Clermont Ferrand, , France

Lille, , France

Lorient, , France

Thonon Les Bains, , France

Valenciennes, , France

Poitiers, , France

Seclin, , France

Arras, , France

La Roche Sur Yon, , France

Amiens, , France

Paris, , France

Arcachon, , France

Armentières, , France

Castres, , France

Lyon, , France

Lyon, , France

Lyon, , France

Mont De Marsan, , France

Montargis, , France

Nice, , France

Paris, , France

Paris, , France

Paris, , France

Paris, , France

Rennes, , France

Rodez, , France

Saint Brieuc, , France

Saint Denis, , France

Saint Malo, , France

Saint Paul, , France

Soyaux, , France

Strasbourg, , France

Strasbourg, , France

Toulouse, , France

Villeneuve Saint Georges, , France

Patients applied

0 patients applied

Trial Officials

Nicolas Grillot, MD

Study Director

Nantes University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported