The Effectiveness of Individualized Imagery Scripts on Sleep, Psychosis, and Suicidality Among Inpatients With Psychosis
Launched by THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER, HOUSTON · Dec 21, 2023
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the use of personalized audio and EEG (a type of brain activity monitoring) technology to help improve sleep for patients with psychosis. The researchers want to find out if using tailored sleep interventions can lead to better sleep quality and reduce symptoms of psychosis, such as hallucinations or feelings of sadness and hopelessness.
To participate in the study, individuals must be diagnosed with a schizophrenia spectrum disorder or a mood disorder that includes psychotic features, and they should have some trouble sleeping, as indicated by specific sleep questionnaires. However, those with substance-induced psychosis, certain cognitive disorders, or those who require constant supervision for safety reasons cannot join. If eligible, participants will be guided through the use of this innovative technology and monitored for any changes in their sleep and mental health over the course of the study. This trial represents a hopeful step toward finding new ways to support patients struggling with sleep issues related to psychosis.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • primary diagnoses of schizophrenia spectrum disorder or mood disorder with psychotic features, as determined by the treatment team or record review
- • capacity to consent to the study as determined by licensed psychologists ( or the primary attending psychiatrist
- • reported sleep dysfunction which will be determined by a subthreshold or more severe score ≥ 8 on the Insomnia Severity Index (ISI), and/or report experiencing nightmares at least once a week.
- Exclusion Criteria:
- • primary substance- or medical-induced psychosis
- • intellectual and developmental disabilities
- • neurodegenerative cognitive disorders
- • implanted devices (e.g., Pacemakers)
- • on one-to-one supervision or 15-minute safety checks for suicidality or aggression
- • patients with roommates that are on 15-minute checks to minimize impact on study participants' awakenings
About The University Of Texas Health Science Center, Houston
The University of Texas Health Science Center at Houston (UTHealth) is a leading academic institution dedicated to advancing health through education, research, and clinical practice. As a prominent sponsor of clinical trials, UTHealth leverages its extensive resources and expertise in biomedical research to facilitate innovative studies aimed at improving patient outcomes. The institution is committed to fostering a collaborative environment that promotes scientific discovery and the translation of research findings into effective healthcare solutions, all while adhering to the highest ethical standards and regulatory guidelines. With a multidisciplinary approach, UTHealth plays a critical role in addressing complex health challenges and enhancing the quality of life in diverse communities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Houston, Texas, United States
Patients applied
Trial Officials
Alia Warner, Ph.D.
Principal Investigator
The University of Texas Health Science Center, Houston
Jessica Badawi, Ph.D.
Principal Investigator
The University of Texas Health Science Center, Houston
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported