Improving Status Epilepticus Treatment Times

Launched by NATIONWIDE CHILDREN'S HOSPITAL · Dec 22, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new way to improve how quickly children with a serious condition called Status Epilepticus (SE) receive treatment while they are in the hospital. SE is when a child has prolonged seizures that last longer than five minutes or multiple seizures without regaining normal brain function in between. The goal of this study is to reduce the time it takes to give children their first dose of a medication called benzodiazepine, which is crucial for stopping these seizures and preventing potential complications.

To be eligible for the trial, children must be between 30 days and 19 years old and experiencing a qualifying episode of SE. However, children with certain types of seizures, like infantile spasms or seizures that don’t have any obvious symptoms, will not be included. Participants in the trial can expect to be part of a study that aims to make seizure treatment faster and more effective, which could help improve their recovery. The trial is currently looking for volunteers, and all genders are welcome to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • SE episode occurs in a male or female child aged between \> 30 days to \< 19 years
• * Seizures meeting AT LEAST ONE of the following criteria:
• • 1. continuous clinically apparent seizure lasting greater than 5 minutes
• • 2. continuous clinically apparent seizure of any duration receiving BZD
• • 3. repeated seizures without return to neurological baseline within 5 minutes
• Exclusion Criteria:
• • SE episode occurs in a child with infantile spasms
• • SE episode occurs in a child with electrographic-only seizures without clinical signs other than encephalopathy