ClinConnect ClinConnect Logo
Search / Trial NCT06196515

Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication

Launched by BRITISH UNIVERSITY IN EGYPT · Dec 25, 2023

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Intracanal Medication

ClinConnect Summary

This clinical trial is studying the effectiveness of a special medication called Nano Calcium Hydroxide to fight bacteria inside the teeth during root canal treatments for permanent molars. The goal is to see if this medication can help improve the treatment for patients suffering from infections related to their tooth roots, known as apical periodontitis.

To participate in this study, you should be a healthy adult between the ages of 21 and 49, without any major health issues or disabilities. You must also have a single permanent molar that shows signs of infection. However, pregnant women, people with weakened immune systems, and those who have taken antibiotics recently, among others, will not be eligible. If you join the trial, you can expect to receive the Nano Calcium Hydroxide treatment during your dental visit, and the research team will monitor your progress to help determine how well it works. This study is currently looking for participants, so if you meet the criteria and are interested, you can learn more about how to get involved.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • healthy males and females.
  • age range between 21-49.
  • patients with no physical disability or psychological problems.
  • patients presenting with single permanent molar with signs and/or symptoms of apical periodontitis, and having Periapican index ≥ 2.
  • Exclusion Criteria:
  • pregnant women.
  • patients with immune-compromised disease.
  • patients with complicated systemic diseases.
  • patients who took antibiotics within a period of 1 month.
  • patients with known sensitivity to the medicaments or pharmaceuticals used in this study.
  • Non-restorable teeth including root fractures, and/or advanced periodontal involvement.

About British University In Egypt

The British University in Egypt (BUE) is a leading academic institution dedicated to advancing research and education in various fields, including healthcare and clinical sciences. As a sponsor of clinical trials, BUE is committed to fostering innovative research that contributes to the understanding and improvement of medical practices. The university collaborates with esteemed local and international partners to ensure rigorous study design, ethical standards, and comprehensive data analysis, ultimately aiming to enhance patient outcomes and contribute to the global medical community. Through its clinical trial initiatives, BUE seeks to bridge the gap between academia and practical application, reflecting its mission to deliver impactful research that benefits society.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Trial Officials

Shehab Eldin M Saber, doctoral

Study Director

British University In Egypt

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported