Safety and Efficacy of XJ-Procedure in Patients With Acute Type A Aortic Dissection Surgery

Launched by FIRST AFFILIATED HOSPITAL XI'AN JIAOTONG UNIVERSITY · Dec 28, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new surgical technique called the "XJ-Procedure" for patients with Acute Type A Aortic Dissection (ATAAD), a serious condition affecting the large blood vessel that carries blood from the heart. The trial aims to compare the safety and effectiveness of the XJ-Procedure combined with the well-known "Sun's procedure" against the traditional suturing method for repairing the aorta during surgery. The goal is to see which method leads to better outcomes for patients undergoing this critical surgery.

To participate in this trial, you need to be between 18 and 70 years old and assessed by a doctor as needing the Sun's procedure for ATAAD. However, there are some conditions that would exclude you from joining, such as having severe problems with the aortic root or other serious health issues. If you qualify and choose to participate, you’ll be randomly assigned to one of the two surgical methods being studied. This trial is currently recruiting participants, and it aims to help improve surgical care for patients with this life-threatening condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18-70 years;
• • Patients with ATAAD attending the relevant department who have been assessed by a clinician as needing "Sun's procedure".
• Exclusion Criteria:
• • Severe aortic root involvement (root diameter \>45 mm, root tear, severe destruction of the aortic root, combined valve disease);
• • Combined coronary artery disease requiring concomitant coronary revascularization;
• • Prior aortic or cardiac surgery;
• • Preoperative severe malperfusion syndromes such as: severe cerebral complications (acute cerebral infarction, cerebral hemorrhage, coma, etc.); malperfusion of abdominal organs or lower extremities \>12 h;
• • Preoperative combination of severe single or multiple organ failure;
• • Pregnant women;
• • Refused to sign the informed consent form and refused to participate in this study.