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Search / Trial NCT06199674

Effects of PBM on Fixed-appliance Orthodontic Patients

Launched by THE UNIVERSITY OF HONG KONG · Dec 29, 2023

Trial Information

Current as of July 27, 2025

Recruiting

Keywords

Photobiomodulation Fixed Appliance Orthodontic Treatment Root Resorption Orthodontic Pain Tooth Movement

ClinConnect Summary

This clinical trial is looking at how a treatment called photobiomodulation therapy (PBM) can help patients who are getting braces. Specifically, the study aims to see if PBM can improve dental health, reduce pain, speed up the closing of gaps in teeth, and affect the bacteria found in dental plaque during orthodontic treatment. The trial is currently recruiting participants aged 18 to 35 who are healthy, have good oral hygiene, and will be having some teeth extracted as part of their orthodontic treatment.

If you join the study, you will receive PBM therapy while undergoing your orthodontic treatment with fixed appliances (like braces). However, there are some important criteria to consider. You will not be eligible if you have serious dental problems, certain health issues, or are currently experiencing root resorption (where the roots of your teeth are being damaged). This trial aims to gather valuable information that could help improve treatment for future orthodontic patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Patients aged between 18 and 35 years old with permanent dentition
  • 2. Patients who undertake orthodontic treatment using fixed appliances
  • 3. Patients who require extraction of premolars in either their upper or lower dental arch
  • 4. Patients who have fair oral hygiene habits
  • 5. Patients who are systemically healthy
  • Exclusion Criteria:
  • 1. Patients with generalized dental caries and severe chronic periodontitis in stages III and IV
  • 2. Patients with congenital or severe craniofacial anomalies which necessitate orthognathic surgery
  • 3. Patients with physical or mental impairment, and those who smoke or undertake systemic medications
  • 4. Patients with current root resorption at any of the teeth
  • 5. Patients with endodontic treatment and/or large restorations on premolars to be extracted

About The University Of Hong Kong

The University of Hong Kong (HKU) is a leading research institution dedicated to advancing medical knowledge and improving healthcare outcomes through innovative clinical trials. With a commitment to excellence in research and education, HKU collaborates with various stakeholders, including healthcare providers and industry partners, to conduct rigorous and ethically sound clinical studies. The university's diverse expertise and state-of-the-art facilities enable it to explore a wide range of therapeutic areas, contributing to the global pursuit of scientific advancement and the development of novel treatment strategies.

Locations

Hong Kong, , Hong Kong

Patients applied

0 patients applied

Trial Officials

Zhiyi Shan

Principal Investigator

The University of Hong Kong

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported