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Search / Trial NCT06201130

Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients.

Launched by NORTHWELL HEALTH · Dec 29, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how changing artificial airways, like tracheostomies and endotracheal tubes, affects the bacteria living in the airways of critically ill children. These devices are often used to help kids with breathing problems, but they can also lead to infections. The researchers want to see if swapping out these artificial airways changes the types and amounts of bacteria present, which could help doctors understand and manage infections better.

To participate, patients must be in the pediatric or neonatal intensive care unit and have either a tracheostomy or an endotracheal tube. There are no specific exclusions, so most children with these devices will be eligible. During the study, researchers will take small samples from the patients' airways before and after the airway is changed, which is a routine and low-risk procedure. This research aims to gather important information that could improve care for children using these life-saving devices.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients with tracheostomies in the pediatric or neonatal intensive care unit
  • Patients with endotracheal tubes undergoing artificial airway exchange in the pediatric or neonatal intensive care unit
  • Exclusion Criteria:
  • None

About Northwell Health

Northwell Health is a leading integrated health system based in New York, dedicated to advancing healthcare through innovative research and clinical trials. With a commitment to improving patient outcomes and enhancing medical knowledge, Northwell Health conducts a diverse range of clinical studies across various therapeutic areas. The organization harnesses its extensive network of hospitals, outpatient facilities, and research institutes to facilitate cutting-edge research, ensuring access to advanced treatments for patients while fostering collaboration among healthcare professionals, researchers, and industry partners. By prioritizing patient-centric approaches and leveraging state-of-the-art technology, Northwell Health aims to drive significant advancements in medical science and public health.

Locations

Queens, New York, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported