Effects of Crossover Point Exercise on Vascular Function of Women in Different Menopausal Years

Launched by BEIJING SPORT UNIVERSITY · Jan 10, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how a specific type of exercise, called Crossover Point Exercise, affects the blood vessel health of women who have gone through menopause. The researchers are looking to understand how exercise can impact vascular function in women at different stages after menopause. To do this, they will enroll postmenopausal women and divide them into four groups: two groups will participate in the exercise program, while the other two will not participate in any exercise training.

To qualify for the study, participants must be postmenopausal women without heart disease, and they should have a body mass index (BMI) that is not too low or too high. Participants will first take a fitness test to measure how well their body uses oxygen and then undergo a three-month exercise program based on their exercise test results. Throughout the trial, researchers will measure various health indicators before and after the exercise program to see how it affects their vascular health. If you or someone you know is interested and meets the eligibility criteria, this could be an opportunity to contribute to important research on women's health.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Postmenopausal women without cardiovascular disease
• Exclusion Criteria:
• • Women with undetermined menopause
• • BMI \<18.5 kg/m2 or BMI \>28 kg/m2
• • fasting plasma triglyceride levels ≥500 mgdl
• • diabetes mellitus or fasting glucose \>140 mgd
• • blood creatinine \>2.0 mgdl
• • uncontrolled hypertension (systolic blood pressure \>160 mmHg and/or diastolic blood pressure \>110 mmHg)
• • untreated thyroid disease
• • life-threatening illness with a prognosis of \<5 years;
• • history of deep vein thrombosis,
• • pulmonary embolism, or breast cancer;
• • currently receiving estrogen therapy.