Effect of Alcohol Consumption on the Success Rates

Launched by JAMIA MILLIA ISLAMIA · Jan 2, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how alcohol consumption affects pain management during dental treatment for a condition called irreversible pulpitis, which is severe inflammation in a tooth's pulp. The study will involve 70 adult patients, with half of them being regular drinkers of alcohol and the other half not drinking at all. Participants will receive an injection of a local anesthetic to numb the area during treatment, and their pain levels will be measured to see if the anesthetic works effectively.

To take part in this trial, you need to have a specific type of tooth problem (symptomatic carious exposed mandibular first or second molars) and fall into one of the two groups based on your alcohol consumption. Eligible participants should be generally healthy, with no major medical issues like heart disease or active infections. If you join the study, you will be monitored closely, and if you feel any pain during the treatment, you’ll be asked to rate it on a simple scale. This research aims to help improve dental care for everyone, especially regarding how alcohol might influence pain relief during dental procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Symptomatic carious exposed mandibular first or second molars.
• • Alcoholic patients: Patient with low-moderate drinking levels according to the US National Institute on Alcohol Abuse and Alcoholism
• • Control patients: No history of alcohol consumption
• • Positive and prolonged response to thermal sensitivity tests and electric pulp test.
• • Vital coronal pulp on access cavity preparation.
• • American Society of Anesthesiologists class I or II medical history.
• • Ability to understand the use of pain scales.
• Exclusion Criteria:
• • Active pain in more than 1 teeth
• • Teeth with fused roots.
• • Radiographic evidence of an extra root.
• • Large restorations with overhanging margins.
• • Full crowns or deep periodontal pockets.
• • Hypertension or cardiovascular diseases, compromised immunity, active infection or inflammation
• • Known allergy or contraindications to any content of the local anesthetic solution or non-steroidal anti-inflammatory drugs (NSAIDs)
• • History of known or suspected drug abuse.
• • Taking any drugs which could affect the pain perception, e.g, opioids, antidepressants, anticonvulsants, muscle relaxants, anxiolytics, sedatives, nsaids. 23
• • Pregnant or breastfeeding patients.
• • Patients with asthma, gastric ulcers, bleeding disorders.