The Impact of Physical Training Under Normobaric Hypoxia on Oxidative Stress Level, Inflammatory State, Intestinal Damage, and Mitochondrial Metabolism in Young Males

Launched by UNIVERSITY SCHOOL OF PHYSICAL EDUCATION, KRAKOW, POLAND · Jan 3, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring how a special training program in a controlled low-oxygen environment, known as normobaric hypoxia, affects young men who are not regularly active. The researchers want to see if this training can improve various health markers, such as inflammation, oxidative stress (which relates to cell damage), and how well the body produces energy, particularly in the gut and muscles. Over four weeks, participants will engage in this training and researchers will track changes in their health and fitness.

To join the study, participants must be healthy young males aged between 18 and 35, with no serious medical conditions or a history of altitude sickness. They should also not change their diet, smoke, or use alcohol or other stimulants during the trial. Those who are eligible will have a thorough medical check-up before starting the program. This study aims to create helpful training guidelines for athletes and coaches, focusing on how to improve performance and recovery through special training techniques.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • no known metabolic diseases, no contraindications to physical exercise and no history of high altitude sickness stated in interview. A medical examination (including ECG, blood and urine tests) is required.
• Exclusion Criteria:
• • changes in diet during the experiment, smoking and abuse of alcohol and/or other stimulants.