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Search / Trial NCT06205251

Diaphragm Structure and Function in Childhood Cancer Survivors

Launched by UNIVERSITY OF MARYLAND, BALTIMORE · Jan 3, 2024

Trial Information

Current as of July 21, 2025

Recruiting

Keywords

Inspiratory Muscle Training Diaphragm Control Of Breathing Muscle Dysfunction Dyspnea

ClinConnect Summary

This clinical trial is looking at how a special training program for breathing muscles can help childhood cancer survivors improve their breathing during exercise. The researchers want to see if this training can make a difference in how these individuals breathe when they are active. If you or someone you know has finished cancer treatment at least a year ago and is a survivor of any type of cancer (except for brain cancer), you might be eligible to participate in this study.

Participants will be involved in a training program focused on strengthening their breathing muscles. They will also be assessed on how well they can breathe during exercise. It's important to note that individuals with certain health issues, such as problems with the heart or lungs, or those who have had recent injuries, may not be able to join the trial. This study is currently recruiting participants, and it aims to help improve the health and quality of life for childhood cancer survivors.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Completed medical treatment (chemotherapy, chemotherapy/surgery, chemotherapy/radiation or any combination of cancer treatment) for any type of cancer, except for cancer of the central nervous system, at least 1 year ago
  • Exclusion Criteria:
  • History of neuromuscular, cardiac, or pulmonary disease prior to the diagnosis of cancer
  • Recent injury or condition (less than 6 months ago) that precludes strength testing or walking
  • Dyspnea with minimal activity (4 on the modified Medical Research Council Dyspnea Scale)

About University Of Maryland, Baltimore

The University of Maryland, Baltimore (UMB) is a leading academic institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, UMB leverages its extensive resources and expertise across various disciplines, including medicine, pharmacy, nursing, and social work, to contribute to groundbreaking discoveries and improve patient outcomes. Committed to ethical research practices and collaboration, UMB fosters an environment that promotes the translation of scientific knowledge into real-world applications, ultimately enhancing the well-being of diverse populations.

Locations

Baltimore, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Simon Ho

Principal Investigator

University of Maryland, Baltimore

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported