Comparison Study Between PET/CT and Whole-Body Diffusion Weighted MRI in the Detection of Distant Malignancies

Launched by SOHAG UNIVERSITY · Jan 4, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at two different medical imaging methods—PET/CT and MRI—to see which one is better at detecting distant cancer spread, known as metastasis. The goal is to find out which method gives clearer and more accurate results for patients who have been diagnosed with various cancers that have spread from their original location.

To be eligible for this study, participants need to have a confirmed cancer diagnosis and evidence that their cancer has spread. However, certain patients cannot participate, such as those who are pregnant, have specific allergies, or have conditions that make MRI scans unsafe, like certain medical devices in their bodies. The trial is not currently recruiting participants, but when it does, those who join can expect to undergo imaging tests to help doctors understand how effective each method is in finding cancer that has spread. This information could help improve cancer detection in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Only patients with malignancies proven by histology and patients with metastatic lesions proven by histopathology or cytology were included.
• Exclusion Criteria:
• • • As regard the PET/CT study, patients who have the general CT contraindications such as pregnancy, breast feeding, history of allergic reaction to the contrast medium, renal disease, etc.
• • As regard the MRI study, general contraindications including claustrophobia, MR-incompatible pacemakers and MR-incompatible heart valves.
• • Patients whose MRI sequences were incomplete, low-quality and/or had no histopathological evidence of metastatic lesions were eliminated from the study.
• • Low-quality or incomplete MRI included MRI exams with incomplete sequence(s), which is particularly common in elderly patients who are unable to tolerate the scan, or uncooperative patients who do not obey breathing instructions and motion artifacts that may impair images and lead to lower accuracy.
• • Declined consent.