The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament

Launched by BRITISH UNIVERSITY IN EGYPT · Jan 12, 2024

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ClinConnect Summary

This clinical trial is studying how effective a medication called diclofenac sodium is at reducing bacteria in the teeth compared to a commonly used treatment called calcium hydroxide paste. Both of these medications will be used inside the canals of permanent molar teeth that have a condition known as chronic apical periodontitis, which is an infection at the tip of the tooth root. The researchers want to find out if diclofenac sodium can work as well as calcium hydroxide for treating this condition.

To participate in the trial, you need to be between 18 and 62 years old and have a tooth diagnosed with apical periodontitis that can be restored. Unfortunately, if your tooth has immature roots, is beyond repair, or if you have certain medical conditions or allergies, you won't be eligible for this study. If you choose to participate, you will be randomly assigned to one of three groups, each receiving a different type of medication. The study is currently looking for volunteers, and if you're interested, you can expect to contribute to important research that could help improve dental treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with teeth diagnosed with apical periodontitis
• • Periapical Index (PAI) ≥ 2
• • The teeth are restorable
• Exclusion Criteria:
• • Teeth with immature roots
• • Non restorable teeth
• • Medically compromised patients with systemic complication that would alter the treatment.
• • Teeth with internal/external root resorption
• • Patient with an allergy to diclofenac sodium