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Search / Trial NCT06207422

The Effects of a Moderate Intensity Training Program Versus a High Intensity Training Program on Central Pain Processing

Launched by UNIVERSITY GHENT · Jan 4, 2024

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Moderate Intensity Training High Intensity Training Pressure Pain Threshold Conditioned Pain Modulation Exercise Induced Hypoalgesia Nociceptive Flexion Reflex Quantitative Sensory Testing

ClinConnect Summary

This clinical trial is studying how different exercise programs can affect how our bodies process pain. Researchers want to find out if a moderate intensity training program (like brisk walking) is as effective as a high intensity training program (like running) in improving pain sensitivity and pain management in healthy individuals. The goal is to learn more about how exercise can help reduce pain sensitivity, which could eventually benefit people with chronic pain conditions.

To participate in this study, you need to be between 18 and 55 years old, have a body mass index (BMI) between 20 and 25, and speak Dutch. You should also have a sedentary job and not exercise more than 3 hours a week. Unfortunately, if you have any current or serious past health issues, including pain complaints or pregnancy, you won't be eligible to join. If selected, participants can expect to engage in an exercise program and help researchers understand the link between physical fitness and pain processing. This research could pave the way for better pain management strategies in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age between 18 and 55 years
  • BMI between 20 and 25 kg/m²
  • Dutch-speaking
  • sedentary job and performing less than 3 hours of moderate physical activity per week
  • Exclusion Criteria:
  • current pain complaints or other (medical and/or psychological) health problems
  • history of serious pain complaints or (medical and/or psychological) health problems
  • history of serious conditions (e.g. cancer, cardiovascular disease, epilepsy, diabetes, depression, etc.)
  • being pregnant
  • pregnant in the past 12 months
  • currently breastfeeding

About University Ghent

University Ghent is a prestigious Belgian research institution renowned for its commitment to advancing medical science and improving patient care through innovative clinical trials. With a multidisciplinary approach, the university fosters collaboration among leading experts in various fields, ensuring rigorous study design and ethical standards. University Ghent is dedicated to exploring new therapeutic modalities and enhancing healthcare outcomes, making significant contributions to both local and global health landscapes. Its state-of-the-art facilities and emphasis on research excellence position it as a pivotal sponsor in the realm of clinical research.

Locations

Ghent, , Belgium

Patients applied

0 patients applied

Trial Officials

Jessica Van Oosterwijck

Principal Investigator

Department of Rehabilitation Sciences, Faculty of Health Sciences, Ghent University, Belgium

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported