Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump

Launched by JAGIELLONIAN UNIVERSITY · Jan 12, 2024

Keywords

ClinConnect Summary

Recent advances in insulin pumps, continuous glucose monitoring (CGM) devices, and control algorithms have resulted in an acceleration of progress in the development of the automated systems of insulin delivery including advanced hybrid closed loop (HCL) insulin pumps. The results of the AHCL insulin pump based studies published so far are very encouraging, including that Medtronic-sponsored study performed at our center "Transition of CSII/CGM naïve patients directly into AHCL (780G) insulin pump: the impact on glucose patterns and quality of life measures" (1-6). Unfortunately there is li...

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Eligibility criteria

• Inclusion Criteria:
• • 1. Age over 65 years
• • 2. T1DM
• • 3. Willing to participate in a study for the specified duration
• • 4. Willing to perform ≥ 4 finger stick blood glucose measurements daily
• • 5. Willing to wear the system continuously throughout the study
• • 6. Glycosylated hemoglobin (A1C) value less than 10.0% at time of screening visit
• • 7. Treated with MDI/CSII (with exclusion of 780G)
• • 8. Willing to perform at least 4 BGM/day, when on MDI/CSII
• • 9. Lack of advanced complications of diabetes, eGFR\>30
• Exclusion Criteria:
• • 1. Severe concurrent illness
• • 2. Laboratory abnormalities, or medications that might affect study participation,
• • 3. Severe renal impairment (eGFR\<30)