PRICO: OPTI Target Range

Launched by CZECH TECHNICAL UNIVERSITY IN PRAGUE · Jan 4, 2024

Keywords

ClinConnect Summary

The PRICO: OPTI Target Range clinical trial is looking at how to better manage oxygen levels in very low birth weight infants (those who weigh less than 3.3 pounds) who are receiving help with breathing in the neonatal intensive care unit (NICU). The study is comparing two different settings for maintaining oxygen levels in the blood: one that is more narrow and precise, and another that is broader. The goal is to find out which method helps these infants breathe better while needing less extra oxygen.

To be eligible for the trial, infants must be at least 14 days old and already receiving respiratory support and oxygen in the NICU. Parents or guardians must provide informed consent, which means they must understand the study and agree to it. If a child qualifies and participates, they can expect to be part of a study that aims to improve the care of very small babies who have breathing difficulties. This research is important as it may help healthcare providers find better ways to support these vulnerable infants in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All VLBW on respiratory support and oxygen requirements after 2 weeks of age in the NICU are eligible after informed consent is obtained.
• Exclusion Criteria:
• • Informed consent is not obtained
• • Recording device for automated control of FiO2 is not available