Neural and Cognitive Consequences of COVID-19 Survival

Launched by SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER · Jan 11, 2024

Keywords

ClinConnect Summary

This clinical trial, named "Neural and Cognitive Consequences of COVID-19 Survival," is investigating the ongoing brain and memory issues that some people experience after recovering from COVID-19. Many individuals report problems like "brain fog," memory difficulties, and fatigue long after their initial infection. Researchers aim to better understand these symptoms by using psychological tests, brain imaging (like MRI), and blood tests to look for signs of brain damage. This study is important for uncovering how COVID-19 affects the brain and what can be done to help those who are struggling with these lingering effects.

To participate in this study, you need to be between 18 and 70 years old and have had a confirmed COVID-19 infection at least three months ago. Since the study includes MRI scans, you must not have any metal in your body, be comfortable in close spaces, and have normal vision. The research will take place in San Francisco and will require some in-person visits to the lab. If you're interested, it’s a chance to contribute to valuable research that could help many individuals dealing with post-COVID cognitive issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Our studies require some in-person visits to our research lab, located at 42nd Ave and Clement St in San Francisco.
• • Because this study includes an MRI, part of the screening process will be to ensure you don't have any metal in your body, you do not have head or neck tattoos, and you are comfortable inside the MRI scanner.
• • 18-70 years with a confirmed COVID infection at least 3 months ago.
• • Negative metal screen for MRI safety
• • Normal (or corrected to normal) vision
• Exclusion Criteria:
• • Past or present neurological problems (including seizures and head trauma resulting in neurological or cognitive symptoms)
• • Loss of consciousness (LOC) greater than 30 minutes or any LOC with neurologic symptoms
• • Major medical conditions (e.g., seizures disorders, treatment with anticonvulsant medication, endocrine disorders, significant cardiac pathology)
• • Substance dependence, within the past year, or failed urine toxicology on the day of neuroimaging sessions
• • Known claustrophobia
• • Current pregnancy
• • IQ estimate \< 70