Staph Intervention for Effective Local Defense

Launched by JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH · Jan 8, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Staph Intervention for Effective Local Defense," is focused on finding ways to reduce Staphylococcus aureus (SA) infections, which are common among Native American communities. The study aims to see if providing education and household supplies, along with a medical treatment, can help lower the number of people carrying SA on their skin. Participants will be divided into two groups: one will receive educational support and supplies only, while the other will also get a biomedical intervention. Researchers will then compare the results from both groups to see which approach is more effective.

To participate in this trial, you need to be a Native American adult aged 18 or older who lives near the WMA Tribal lands and has been confirmed to carry SA. It's important that you have certain risk factors for SA infections, such as having diabetes or a higher body weight. If you join the study, you can expect to receive support and guidance to help reduce your risk of SA infections. However, individuals with certain allergies, recent antibiotic use, or current SA infections will not be eligible. This study is currently recruiting participants, so if you meet the criteria, you could play an important role in improving health in your community.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Native American adult living on or adjacent to the WMA Tribal lands
• • 18 years of age and older
• • Lab-confirmed SA carriage at time of enrollment
• • Ability to provide written informed consent
• • Ability to comply with follow-up activities
• • Risk factor for SA-associated infection: Diagnosed with diabetes OR body mass index ≥30 OR documented SSTI or SA infection in the past 3 years
• Exclusion Criteria:
• • Immediate family member of study staff
• • Allergy to citrus or any ingredient in Nozin, Hibiclens, or mupirocin
• • Without a permanent home (e.g., living in a group home, shelter, or is unhoused)
• • Use of antibiotics within 30 days prior to the first study visit (time-limited)
• • Current SA infection (time-limited)