Autonomic Dysreflexia in Spinal Cord Injuries: UDS Filling Speed Impact

Launched by PUSAN NATIONAL UNIVERSITY YANGSAN HOSPITAL · Jan 8, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a condition called Autonomic Dysreflexia (AD), which can occur in people with spinal cord injuries. The researchers want to learn how the speed at which the bladder fills with liquid affects the occurrence and characteristics of AD. They will look at patients who have had a spinal cord injury for at least six months and who have experienced AD due to a full bladder in previous tests. The goal is to find out whether the way the bladder expands or the rate of filling has a bigger effect on AD symptoms.

To be eligible for this trial, participants must have a specific type of spinal cord injury at a certain level (between C1 and T6) and be classified as AIS A or B, which relates to the severity of their injury. However, people with very high blood pressure during testing, those who are unstable due to other health issues, or those with a urinary tract infection cannot participate. If someone is eligible and chooses to join, they will undergo tests to help the researchers gather important information about AD and bladder function.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with chronic spinal cord injury 6 months after receiving the award
• • 2. Patients with confirmed AD due to bladder fullness in previous urodynamic test
• • 3. Patients confirmed to have neurological damage level C1-T6, AIS A or B
• Exclusion Criteria:
• • 1. Patients who cannot perform the test because their systolic blood pressure remains at 150 mmHg during the urodynamic test
• • 2. Patients who cannot undergo testing due to hemodynamic instability
• • 3. Patients who cannot undergo testing due to overt urinary tract infection