Neurofeedback-EEG Rehabilitation Protocol on Motor Recovery in the Subacute Phase Post-stroke (CUSTOM-NF-STROKE)

Launched by UNIVERSITY HOSPITAL, TOULOUSE · Jan 8, 2024

Keywords

ClinConnect Summary

The CUSTOM-NF-STROKE clinical trial is studying a technique called neurofeedback (NF) to help improve movement recovery in patients who have had a stroke. Neurofeedback involves providing real-time feedback to patients about their brain activity while they perform tasks, which helps them learn to control their brain functions better. This trial is comparing a standard NF method with a personalized NF approach that is tailored to each patient's needs and preferences based on their responses to questionnaires.

To participate in this study, you must be an adult over 18 years old who has experienced a stroke and has difficulty moving one side of your body (known as hemiplegia). You should be between 15 days and 6 months post-stroke and able to sit comfortably for about an hour. If you join the trial, you can expect to engage in NF sessions aimed at helping you improve your motor skills. This research is currently recruiting participants, and it’s important to note that certain conditions, like severe epilepsy or specific neurological issues, may prevent you from being eligible.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Man, woman, over 18 years old
• • Motor deficit of the upper limb type of hemiplegia, secondary to a hemorrhagic or ischemic stroke authenticated by brain imaging (MRI or CT)
• • Post-stroke patients in the subacute phase, between 15 days and 6 months after the stroke
• • Correct or corrected vision allowing reading at a distance of 0 to 2m
• • Ability to maintain a seated position for 1 hour
• • Patient affiliated to a social security scheme or beneficiary of such a scheme
• • Informed patient having signed consent
• Exclusion Criteria:
• • Minors (age \< 18 years)
• • Phasic disorder limiting comprehension corresponding to a Boston Diagnostic Aphasia Examination (BDAE) score \< 4
• • Attentional disorder not allowing sufficient attention to be maintained for 1 hour
• • History of known stroke with motor sequelae.
• • Known peripheral neurological pathology affecting the paretic upper limb.
• • Other known central neurological pathology
• • Factors hindering EEG acquisition (scalp pathology, abnormal cervico-cephalic movements, cranial metal implants)
• • Unstabilized epilepsy
• • Refusal to participate in the study
• • Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision
• • Pregnant, parturient, or breastfeeding patient