A Direct-to-Consumer Study Investigating the Effect of Specific Cannabinoid Products on Motivation, Energy Level, Focus, and Appetite in Healthy Adults

Launched by PHYLOS BIOSCIENCE, INC. · Jan 16, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a special cannabinoid called Tetrahydrocannabivarin (THCV) on motivation, energy levels, focus, and appetite in healthy adults. Researchers want to see if THCV can help people feel more energetic and focused without increasing their appetite, which is different from other cannabis products that can make you feel hungry. The trial is based on reports from cannabis users who found THCV to be uplifting and energizing.

To participate, you need to be a healthy adult over 21 years old, live in the Greater Los Angeles area, and be familiar with using cannabis. Participants should be able to focus in their daily activities, have a smartphone to download a study app, and be willing to avoid alcohol and THC products during the study. If you join, you can expect to complete assessments over about 14 days to help researchers understand how THCV affects your motivation and focus. It's important to note that those with certain health conditions or medication use may not be eligible for the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Healthy adults age \> 21 years old
• • 2. Work / study / play in an environment that requires focus
• • 3. Able to read and understand English
• • 4. Able to read, understand, and provide informed consent
• • 5. Able to use a personal smartphone device and download Chloe by People Science
• • 6. Able to complete study assessments over the course of up to 14 days
• • 7. Familiar with the use of cannabis and its effects
• • 8. Able to tolerate at least 5mg THC
• • 9. Willingness to abstain from use of any THC containing products during study product use days
• • 10. Willingness to abstain from use of alcohol during study product use days
• • 11. Greater Los Angeles area residents only
• Exclusion Criteria:
• • 1. Participants who do not have a smartphone and/or internet access
• • 2. Any known adverse effects from taking cannabis
• • 3. Concomitant Therapies: Currently taking medication for ADHD or psychotropic medications
• 4. Other Illnesses or Conditions: Participants who have the following co-morbidities are excluded:
• • 1. History or currently undergoing product use for substance abuse disorders
• • 2. Currently pregnant, planning to become pregnant within the next month, or breastfeeding
• • 3. Allergies to formulation ingredients
• • 4. Current or prior psychotic disorder
• • 5. Immunosuppressive product uses, including organ transplant participants, active immunotherapy for cancer product use
• • 6. Any condition that is considered by investigator to be a contraindication to cannabis (e.g. specific drug-use interaction, unstable cardiac arrhythmia)