Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity

Launched by UNIVERSITY OF SOUTH ALABAMA · Jan 9, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how a dietary supplement called nicotinamide riboside might help protect against the harmful effects of acetaminophen, a common pain reliever found in products like Tylenol®. Researchers are particularly interested in this because astronauts often use acetaminophen for pain relief, and they want to understand how it might affect their health in space. The study will compare the levels of harmful chemicals in urine after volunteers take acetaminophen alone versus taking it with the dietary supplement. They will also check how these chemicals behave under conditions similar to those in space.

To participate in this study, you should be between the ages of 65 and 74 and not allergic to acetaminophen or nicotinamide riboside. If you join, you'll take a tablet of acetaminophen, and some of you will also take the dietary supplement. The research team will then collect urine and blood samples to see how these substances interact. This information could help improve safety for astronauts and others who use acetaminophen. The trial is currently recruiting participants, so if you meet the criteria and are interested, you could play a vital role in this important research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • n/a
• Exclusion Criteria:
• • Individual allergic to acetaminophen or nicotinamide riboside