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Search / Trial NCT06215404

Fluid Management Strategies on Blood Loss in Liver Transplantation

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Jan 10, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Fluid Management Blood Loss

ClinConnect Summary

This clinical trial is studying how different fluid management strategies during liver transplantation can affect bleeding and recovery. The main goal is to compare two approaches: one that limits the amount of fluid given to patients (restrictive) and another that allows more fluid (liberal). Researchers want to see how these strategies influence bleeding during surgery and the effects on important organs, like the lungs and kidneys, after the operation. They will use a special monitoring device to track how much fluid is needed and how it impacts patients.

To participate in this trial, individuals should be between 18 and 75 years old and have severe liver disease that requires a liver transplant. However, those with heart rhythm problems (arrythmias) cannot join. If eligible, participants can expect to be randomly assigned to one of the two fluid management groups during their surgery. The results of this study could help determine the best way to manage fluids in liver transplant surgery, potentially improving outcomes for patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • end stage liver disease
  • age between 18y/o to 75 y/o
  • expected to recieve to receive liver transplantation
  • Exclusion Criteria:
  • arrythmia

About National Taiwan University Hospital

National Taiwan University Hospital (NTUH) is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a pioneer in medical education and patient care in Taiwan, NTUH integrates cutting-edge technology with comprehensive clinical expertise to facilitate groundbreaking studies across various medical fields. The hospital’s dedicated research team collaborates with local and international partners to enhance the understanding of diseases and improve treatment outcomes. By prioritizing patient safety and ethical standards, NTUH strives to contribute to the global medical community and foster advancements in healthcare practices.

Locations

Taipei, , Taiwan

Patients applied

0 patients applied

Trial Officials

Kuang-Cheng Chan, M.D.,PhD.

Principal Investigator

Department of Anesthesiology, National Taiwan University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported