Adaptive Radiotherapy in Head and Neck Tumor Patients
Launched by UNIVERSITY HOSPITAL, ESSEN · Jan 19, 2024
Trial Information
Current as of July 12, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at a new type of radiation therapy called dysphagia-optimized intensity-modulated radiotherapy (DO-IMRT) for patients with cancers in the throat, specifically oropharyngeal and hypopharyngeal cancers. The goal is to see if this method can reduce radiation exposure to areas that affect swallowing while still treating the cancer effectively. By doing this, researchers hope to improve patients' ability to swallow and their overall quality of life compared to standard radiation therapy.
To participate in this trial, patients should be between the ages of 65 and 74, have a good performance status (meaning they can carry out daily activities), and should not have received prior cancer treatment. Participants can expect to receive either the new DO-IMRT or the standard treatment, with the chance to help improve future care for others with similar conditions. This study is still recruiting participants, and it aims to set a new standard for how we treat pharyngeal cancer while minimizing side effects like difficulty swallowing.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • ECOG 0/1 No prior cancer treatment
- Exclusion Criteria:
- • ECOG 2-4 Prior cancer treatment
About University Hospital, Essen
The University Hospital Essen is a leading academic medical center dedicated to advancing healthcare through innovative research and comprehensive clinical services. As a prominent sponsor of clinical trials, the hospital leverages its extensive expertise in various medical disciplines to facilitate cutting-edge studies aimed at improving patient outcomes. With a commitment to scientific excellence and patient safety, the University Hospital Essen collaborates with a network of researchers and healthcare professionals to explore new therapies and treatment modalities, contributing significantly to the field of medicine and enhancing the overall quality of care.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Essen, , Germany
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported