A Computerized Depression Intervention in Veterans

Launched by VA OFFICE OF RESEARCH AND DEVELOPMENT · Jan 11, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new online program called Deprexis, designed to help Veterans dealing with mild to moderate depression. The goal is to see if this self-guided internet intervention can improve their mental health and daily functioning. Many Veterans struggle with depression, and getting help quickly can make a big difference in their lives. In this study, some participants will use Deprexis for eight weeks, while others will continue with their usual treatment. Researchers want to find out how well Deprexis works and if Veterans find it helpful and easy to use.

To participate in the trial, Veterans must be between the ages of 65 to 74 and should have access to the internet through a computer, tablet, or smartphone. They also need to be stable on their current depression medications and not have severe depression. Those with certain mental health issues, like active symptoms of psychosis, Bipolar I Disorder, or current suicidal thoughts, will not be eligible. Overall, this study is important because it could provide Veterans with a convenient and effective way to get support for their depression, improving their quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Potential participants include male and female Veterans of all races/ethnicities who are:
• • able to comprehend and sign the informed consent form
• • have reliable access to the internet and a computer, tablet and/or smartphone
• • exhibit mild or moderate, but not very severe, levels of depression
• • stable on psychotropic medications
• Exclusion Criteria:
• Aim 1 and Aim 2: Veterans will be excluded from study participation if they:
• • endorse any positive symptoms of a psychotic disorder
• • screen positive for Bipolar I Disorder
• • report current suicidal risk