Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan

Launched by KHON KAEN UNIVERSITY · Jan 22, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether a low dose of a medication called propofol can help prevent a condition known as emergence agitation in young children after they wake up from anesthesia. Emergence agitation is when children become confused, upset, or agitated as they come out of anesthesia, which can happen after a procedure like an MRI scan. In this study, children aged 2 to 8 years who are scheduled to have an MRI under a type of anesthesia called sevoflurane will receive either propofol or a placebo (a saline solution that has no active medication) after their scan to see if it helps reduce these symptoms.

To be eligible for this trial, children must be between 2 and 8 years old and have no serious health issues. Some conditions, such as developmental delays or certain allergies, may exclude them from participating. If a child joins the study, their parents can expect that after the MRI, they will receive either the propofol or placebo, and the researchers will observe how the child behaves as they wake up from anesthesia. This trial aims to find out if propofol is a helpful option for managing emergence agitation in young patients.

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ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 2-8 years
• • ASA class I or II ,who schedule for MRI scan under sevoflurane anesthesia
• Exclusion Criteria:
• • Developmental delay
• • Psychological and neurological disorders
• • Abnormal airway
• • Reactive airway disease
• • Allergy to propofol, egg product
• • Family history of malignant hyperthermia
• • Need iv sedative medication before induction
• • Obesity