Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women

Launched by DHURAKIJ PUNDIT UNIVERSITY · Jan 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a natural substance called phytoestrogen from the plant Pueraria Mirifica on improving cholesterol and fat levels in the blood of postmenopausal women. The researchers want to find out if taking Pueraria Mirifica can lower harmful fats and cholesterol while increasing good cholesterol. Participants will take capsules containing Pueraria Mirifica twice a day for two months, while also following dietary and lifestyle guidelines.

To be eligible for this study, women need to be postmenopausal for over a year and have abnormal cholesterol or fat levels in their blood. However, those who have taken certain medications or have specific health issues, like diabetes or a history of cancer, cannot participate. If you join the trial, you can expect regular check-ins to monitor your health and see how the treatment is working. This study aims to provide valuable information that could help improve heart health in women after menopause.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Natural menopause, last menstrual period more than one year ago.
• 2. Abnormal lipid profile parameters The criteria set for this research are:
• • LDL\>130 mg/Dl or
• • TG\>150 mg/Dl or
• • Total cholesterol\>200 mg/Dl or
• • HDL-C less than 50 mg/Dl. (Latest blood results not more than 6 months)
• • 3. Willing to participate in the project
• Exclusion Criteria:
• • 1. Have ever received lipid-lowering medication or hormone replacement therapy or SERMs. During the past 6 weeks
• • 2. have had surgery on the ovaries or uterus before
• • 3. have a history of cancer within a 5-year period
• • 4. have diabetes or uncontrolled high blood pressure, including HbA1c \>9, Systolic blood pressure \>180 or Diastolic blood pressure \>110
• • 5. Endocrine system disease such as thyroid
• • 6. Ever had an organ transplant
• • 7. Regularly use drugs, marijuana, or drink alcohol.
• • 8. has a psychiatric disorder
• • 9. have other serious medical conditions that require close monitoring
• • 10. Inconvenient to follow up until the end of the research.