Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent Hypoparathyroidism

Launched by AARHUS UNIVERSITY HOSPITAL · Jan 20, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether a special imaging technique called autofluorescence (AF) can help reduce the risk of hypoparathyroidism after surgery for thyroid cancer. Hypoparathyroidism is a condition that can occur when the parathyroid glands are accidentally damaged during thyroid surgery, leading to low calcium levels in the body. The trial is looking at patients who will undergo either a total thyroidectomy (removal of the entire thyroid) or a completion thyroidectomy (removal of the remaining part of the thyroid) to see if using AF during surgery makes a difference.

To be eligible for the trial, participants must be over 18 years old, have been diagnosed with or suspected to have thyroid cancer, and be scheduled for one of the types of thyroid surgery mentioned. They should also have normal calcium levels before the surgery. The trial is currently recruiting participants, and everyone is welcome to join regardless of gender. Those who take certain medications or have specific kidney conditions may not qualify. Participants can expect to receive careful monitoring during and after their surgery to assess the effectiveness of the imaging technique in preventing hypoparathyroidism.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age\>18 years and able to give informed consent.
• • Suspicion or diagnosis of thyroid cancer.
• • Planned total thyroidectomy or completion thyroidectomy.
• • Normocalcemia prior to surgery.
• Exclusion Criteria:
• • Planned simultaneous parathyroid surgery.
• • Treatment with active vitamin D analogues.
• • eGFR \< 30.