The Role of Pharmaco-mechanical Thrombectomy in Management of Acute Lower Extremity Arterial Ischemia

Launched by ASSIUT UNIVERSITY · Jan 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment approach for people with acute lower extremity arterial ischemia, a condition where blood flow to the legs is suddenly reduced, which can cause severe pain and tissue damage. The researchers want to see if a combination of techniques, including using a balloon to break up blood clots and a special device called an angiojet to help clear the blockage, can be effective. This method aims to restore blood flow quickly while minimizing risks associated with traditional treatments that involve long-term medication or major surgery.

To participate in this trial, individuals must be at least 18 years old and have experienced symptoms of limb ischemia within the last two weeks, or within the last month for a slightly different type of ischemia. However, those with certain conditions, like irreversible limb damage or who are pregnant, cannot take part in the study. Participants will be closely monitored throughout the trial, and the team will provide detailed information about what to expect during the treatment process. This trial is currently recruiting participants, and it offers an opportunity to contribute to potentially improved care for this serious condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Symptom onset within 14 days for acute limb ischemia or within 30 days for subacute limb ischemia due to embolic or thrombotic occlusion of a native arteries, bypass graft, or arterial stent.
• • Rutherford category I, IIa or IIb
• Exclusion Criteria:
• • ALLI secondary to dissections, vasculitis, and/or target vessel trauma
• • Pregnancy or positive pregnancy test
• • Rutherford category III Irreversible (neglected) limb ischemia
• • patients allergic to contrast agent,
• • serum creatine\>300 mmol/L